Summary: The largest exome-sequencing study of schizophrenia to date has uncovered eight new genes tied to the disorder. Two genes, STAG1 and ZNF136, were strongly implicated, while six others showed…
Tag: mental health
Highly Sensitive People Face Greater Mental Health Risks
Summary: A large-scale meta-analysis of 33 studies has shown that highly sensitive individuals are more prone to common mental health problems, including depression, anxiety, PTSD, and avoidant personality disorder. Sensitivity…
Bipolar Mood Shifts Linked to Insulin Signaling in the Pancreas
Summary: A new study uncovers a pancreas–hippocampus feedback loop that may help explain mood swings in bipolar disorder. Using patient-derived pancreatic islets, researchers found reduced insulin secretion linked to elevated…
Brain Circuit Model Reveals How Striatum Shapes Everyday Decisions
Summary: Researchers have developed a computational framework that maps how the striosomal compartment of the striatum governs everyday decision-making. By integrating biology, decision theory, and mathematical modeling, the study reveals…
When Gut Rhythms Over-Sync With the Brain, Mental Strain Rises
Summary: A large-scale study has found that unusually strong coordination between brain activity and the stomach’s slow, rhythmic waves may signal greater mental distress. Using fMRI and electrogastrography on more…
Youth athletes, not just professionals, may face mental health risks from repeated traumatic brain injuries
On July 28, 2025, a 27-year-old gunman entered a New York City office building that is home to the National Football League’s headquarters. He shot and killed four people and…
Brain Reward Signals Blunted by Genetic Depression Risk
Key Questions Answered Q: How does genetic risk for depression affect the brain?A: Young adults with a higher genetic predisposition to depression showed reduced brain activity in key areas linked…
Fat Molecule May Control How You Feel Emotion
Key Questions Answered Q: What did researchers discover about the serotonin 5-HT1A receptor?A: They mapped how it activates different brain signaling pathways, offering insight into how mood and emotion are…
Murder-Suicide Rates in U.S. Higher Than Previously Estimated
Key Questions Answered Q: How common are murder-suicide events in the U.S.?A: The study found an average of 820 deaths per year from murder-suicide events—higher than previous estimates. Q: Who…
New Drug Targets Brain Glial Cells to Reverse PTSD Symptoms
Key Questions Answered Q: Why do PTSD patients struggle to forget traumatic memories?A: The study reveals that excessive GABA, produced by astrocytes via the MAOB enzyme, disrupts the brain’s ability…