Summary: New research suggests that fluoxetine, commonly used as an antidepressant, may also help protect against infections and sepsis. Scientists found that the drug has antimicrobial properties and helps regulate…
Tag: neuropharmacology
How CBD Modulates THC’s Impact on the Brain
Summary: Researchers have identified how CBD interacts with cannabinoid receptors to mitigate the negative effects of THC, the psychoactive component of cannabis. Unlike THC, which fully activates the receptor and…
GLP-1 Drugs Offer Brain Benefits but May Pose Other Health Risks
Summary: A study analyzing data from over 2 million veterans found that GLP-1 receptor agonists, popular weight-loss drugs like Ozempic and Wegovy, provide significant neurological and behavioral health benefits, including…
How Conscious Thought Fades Under Anesthesia
Summary: A new study has shown that conscious thought relies on synchronized brain rhythms to maintain communication between sensory and cognitive brain regions. Under general anesthesia, this rhythm-based communication breaks…
Dual-Targeting Drug Halts Tau Accumulation in Alzheimer’s
Summary: Scientists have developed a drug that targets both major aggregation-promoting sites of the Tau protein, a key player in Alzheimer’s disease. This peptide inhibitor, RI-AG03, effectively prevents Tau buildup…
Alzheimer’s Drug Faces Scrutiny Over Safety, Efficacy Concerns
Summary: The FDA-approved Alzheimer’s drug donanemab is under scrutiny due to concerns about its effectiveness and safety, according to an investigation. The study highlights multiple patient deaths during trials, design…
No Link Found Between Ozempic and Suicide Risk
Summary: A new study has found no evidence that GLP-1 analogues, common diabetes drugs, increase the risk of suicide, self-harm, or related mental health issues. Researchers analyzed data from around…
Morphine’s Pain Relief Mechanism Unveiled
Summary: Researchers have uncovered how morphine relieves pain by activating a specific group of neurons in the brain, termed the ‘morphine ensemble.’ These neurons, located in the rostral ventromedial medulla…
Adjusting Proteins Increases Ozempic’s Effectiveness
Summary: Adjusting melanocortin proteins in the brain enhances the effectiveness of GLP-1 diabetes and weight-loss drugs. By inhibiting MC3R or activating MC4R, mice showed increased sensitivity to these drugs, leading…
Immunotherapy Shows Promise as Alzheimer’s Treatment
Summary: Researchers unveiled a novel approach to combat Alzheimer’s disease by activating microglia, the brain’s immune cells, to devour amyloid beta plaques, a hallmark of the condition. This study highlights…
