Summary: Researchers have discovered that nitrous oxide can safely enhance the delivery of gene therapy to the brain by making the blood-brain barrier (BBB) more permeable when paired with focused…
Tag: neuropharmacology
Vitamin B1 Derivative Sparks Dopamine, Boosts Wakefulness
Summary: Thiamine derivatives, once developed to treat nutrient deficiencies, are now being explored for their potential effects on brain function and energy. A new study shows that TTFD, a thiamine…
Potential Depression Risk Linked to Ozempic-Like Drugs
Summary: A new international study reveals a possible connection between GLP1 receptor agonists—used in drugs like Ozempic—and increased risk of depression and suicidal ideation, especially in people with low dopamine…
Prozac Shows Promise in Fighting Infections & Sepsis
Summary: New research suggests that fluoxetine, commonly used as an antidepressant, may also help protect against infections and sepsis. Scientists found that the drug has antimicrobial properties and helps regulate…
How CBD Modulates THC’s Impact on the Brain
Summary: Researchers have identified how CBD interacts with cannabinoid receptors to mitigate the negative effects of THC, the psychoactive component of cannabis. Unlike THC, which fully activates the receptor and…
GLP-1 Drugs Offer Brain Benefits but May Pose Other Health Risks
Summary: A study analyzing data from over 2 million veterans found that GLP-1 receptor agonists, popular weight-loss drugs like Ozempic and Wegovy, provide significant neurological and behavioral health benefits, including…
How Conscious Thought Fades Under Anesthesia
Summary: A new study has shown that conscious thought relies on synchronized brain rhythms to maintain communication between sensory and cognitive brain regions. Under general anesthesia, this rhythm-based communication breaks…
Dual-Targeting Drug Halts Tau Accumulation in Alzheimer’s
Summary: Scientists have developed a drug that targets both major aggregation-promoting sites of the Tau protein, a key player in Alzheimer’s disease. This peptide inhibitor, RI-AG03, effectively prevents Tau buildup…
Alzheimer’s Drug Faces Scrutiny Over Safety, Efficacy Concerns
Summary: The FDA-approved Alzheimer’s drug donanemab is under scrutiny due to concerns about its effectiveness and safety, according to an investigation. The study highlights multiple patient deaths during trials, design…
No Link Found Between Ozempic and Suicide Risk
Summary: A new study has found no evidence that GLP-1 analogues, common diabetes drugs, increase the risk of suicide, self-harm, or related mental health issues. Researchers analyzed data from around…
