Summary: An epidemiological investigation from Durham University reveals that the mental health benefits linked to classic psychedelics, such as psilocybin and LSD, vary significantly across human lifespans. Published in Scientific…
Tag: Psychedelics
Single-Dose Psilocybin Lacks Lasting Behavioral Effects
Summary: A coordinated multi-laboratory investigation published in Nature Neuroscience challenges widespread assumptions regarding the enduring behavioral benefits of psychedelic compounds in animal models. Neuroscientists across five independent laboratories at UC…
Psilocybin Replaces Lost Synapses in Depressed Brains
Summary: A neuroimaging and genetic investigation led by researchers at the University of California, Santa Cruz, reveals precisely how psilocybin restructures neural connectivity in living brains. Publishing in Nature Neuroscience,…
LSD Microdosing Enhances Sustained Attention in Women
Summary: A pilot study reveals that low doses of LSD significantly improve sustained attention and reduce attention lapses in women, while producing no comparable cognitive enhancement in men. The preliminary…
Why Psychedelics Make Everything Feel Deeply Connected
Summary: Researchers introduce “apical hypercontextualisation”—a bottom-up neurobiological mechanism explaining how psychedelics (psilocybin, LSD, DMT, mescaline) transform perception and cognition. Moving beyond macro-scale whole-brain neuroimaging, the framework focuses on the cellular…
Psychedelics and Ketamine Rewire Brain Immune Signals in Depression
Summary: A study uncovered a novel neuroimmune mechanism explaining how rapid-acting antidepressants, including ketamine and psychedelics, alleviate treatment-resistant depression. Despite acting on different initial neural receptors, these distinct fast-acting therapeutics…
Psilocybin Therapy Drives 75% PTSD Remission
Summary: The first U.S. clinical trial evaluating psilocybin-assisted therapy in military veterans with treatment-resistant post-traumatic stress disorder (PTSD) has demonstrated significant safety and clinical efficacy. The 11-week pilot trial combined…
Psychedelic Trips Can Halt Political Hate
Summary: A massive study tracking 21,990 U.S. adults has demonstrated that the specific cultural and political atmosphere surrounding a psychedelic experience can systematically pivot its psychological aftermath. Participants whose most…
Single Psilocybin Dose Sparks Rapid Depression Remission
Summary: A Phase 2 randomized clinical trial demonstrates that a single 25 mg dose of psilocybin, combined with psychotherapeutic support, provides rapid, statistically significant, and clinically meaningful reduction in symptoms…
Psychedelics Remodel Myelin to Heal PTSD
Summary: For years, scientists have focused on how psychedelics “rewire” neurons. But a groundbreaking study has found a “missing link” in long-term PTSD recovery: myelin remodeling. Researchers discovered that psilocybin…
