Astrocyte Disruption Tied to Depression After Childhood Stress

Summary: Researchers have shown that astrocytes in the lateral hypothalamus play a pivotal role in how stress shapes behavior, particularly after early-life adversity. In mice, stress led to smaller, less…

Sex Shapes the Course of Bipolar Disorder and Schizophrenia

Summary: A large multicenter study has revealed that sex influences the course and characteristics of schizophrenia and bipolar disorder. Women with schizophrenia tended to begin treatment later, while men with…

Chronic Stress Sends Immune Cells to Brain, Driving Depression

Summary: A new study shows that chronic stress causes immune cells called neutrophils to leave bone marrow in the skull and collect in the brain’s protective membranes, where they contribute…

Depression Disrupts Learning to Avoid Unpleasant Events

Summary: Depression specifically impairs the ability to learn how to actively avoid unpleasant events, though it does not affect avoidance behavior once learned. Researchers tested 465 participants across a range…

Extreme Heat Makes People More Negative

Summary: A large-scale global study shows that extreme heat affects not just our bodies, but also our emotions. Researchers analyzed over a billion social media posts and found that when…

Music Sparks Social Imagination and Eases Loneliness

Summary: A large-scale study with 600 participants shows that music can genuinely evoke feelings of companionship by sparking social imagination. When participants listened to folk music, they imagined vivid social…

Hormonal Contraceptives Influence Memory of Emotional Events

Summary: A new study reveals that hormonal contraceptives may shape both emotional responses and memory processing in women. Compared with naturally cycling women, users of hormonal birth control had stronger…

Brain Cells Behind Depression Identified

Summary: Researchers analyzing post-mortem brain tissue found two cell types altered in people with depression: excitatory neurons that regulate mood and stress, and microglia that manage inflammation. The findings highlight…

The Midlife “Unhappiness Hump” Has Vanished, But at a Cost

Summary: A new large-scale study finds that the long-observed “unhappiness hump,” where mental distress peaked in midlife, has disappeared. Instead, younger people now report the highest levels of anxiety, depression,…

Big Five No More? New Study Uncovers Hidden Personality Traits

Summary: For 40 years, the Big Five personality model has dominated psychology, but new research suggests it may be incomplete. Using taxonomic graph analysis, researchers mapped personality from the ground…