High-THC Cannabis Linked to Psychosis and Addiction

Summary: A systematic review of nearly 100 studies found that high-THC cannabis products are linked to negative mental health outcomes, particularly psychosis, schizophrenia, and cannabis use disorder. While some therapeutic…

Brain Study Reveals Circuit Controlling Depression and Anxiety

Summary: A new study identifies brain area 46 in the marmoset dorsolateral prefrontal cortex as a key regulator of mood-related behavior. When this region was inactivated, the animals showed less…

How Stress Types Differently Impact Brain and Behavior

Summary: Stress is a universal experience, but not all stress affects the brain in the same way. A new study in rats reveals that acute stress provokes anxiety-like behaviors, especially…

Eight New Genes Linked to Schizophrenia Revealed

Summary: The largest exome-sequencing study of schizophrenia to date has uncovered eight new genes tied to the disorder. Two genes, STAG1 and ZNF136, were strongly implicated, while six others showed…

Highly Sensitive People Face Greater Mental Health Risks

Summary: A large-scale meta-analysis of 33 studies has shown that highly sensitive individuals are more prone to common mental health problems, including depression, anxiety, PTSD, and avoidant personality disorder. Sensitivity…

Bipolar Mood Shifts Linked to Insulin Signaling in the Pancreas

Summary: A new study uncovers a pancreas–hippocampus feedback loop that may help explain mood swings in bipolar disorder. Using patient-derived pancreatic islets, researchers found reduced insulin secretion linked to elevated…

Brain Circuit Model Reveals How Striatum Shapes Everyday Decisions

Summary: Researchers have developed a computational framework that maps how the striosomal compartment of the striatum governs everyday decision-making. By integrating biology, decision theory, and mathematical modeling, the study reveals…

When Gut Rhythms Over-Sync With the Brain, Mental Strain Rises

Summary: A large-scale study has found that unusually strong coordination between brain activity and the stomach’s slow, rhythmic waves may signal greater mental distress. Using fMRI and electrogastrography on more…

Youth athletes, not just professionals, may face mental health risks from repeated traumatic brain injuries

On July 28, 2025, a 27-year-old gunman entered a New York City office building that is home to the National Football League’s headquarters. He shot and killed four people and…

Brain Reward Signals Blunted by Genetic Depression Risk

Key Questions Answered Q: How does genetic risk for depression affect the brain?A: Young adults with a higher genetic predisposition to depression showed reduced brain activity in key areas linked…