Combining Cannabis and Tobacco Triples Psychosis Risk

Summary: A multi-site study reveals that combining cannabis and tobacco, a trend known as “co-use”, significantly increases the long-term risk of developing full psychotic disorders like schizophrenia. The study tracked…

Genetic Pathways Link Cannabis Use to Psychosis Risk

Summary: New research provides a breakthrough in understanding the biological mechanisms linking Cannabis Use Disorder (CUD) and psychosis. By conducting a large-scale genetic meta-analysis, researchers identified over 500 genetic loci…

Map of Brain Histamine System Links Molecule to ADHD and Depression

Summary: Researchers developed the first multiscale map of the brain’s histamine system, spanning from genetics to behavior. While histamine is famously linked to allergies, this study highlights its critical, often-overlooked…

ADHD Medication May Shield Against Psychosis

Summary: A major study has found that treating ADHD with stimulant medication during childhood may actually lower the long-term risk of developing serious psychotic disorders, such as schizophrenia. The research…

Teenage Cannabis Use Linked to 52% Higher Schizophrenia Risk

Summary: New research reveals a striking age-dependent link between cannabis use and mental health. The study found that teenagers with cannabis use disorder (CUD) face a significantly higher risk of…

Brain’s Clogged Pipes: A Surprising New Link to Hallucinations

Summary: Schizophrenia and related psychotic disorders are often preceded by “silent” brain vulnerabilities long before symptoms like hallucinations emerge. A groundbreaking study has identified a potential culprit: the glymphatic system,…

Chatbots Can Worsen Delusions and Mania

Summary: For many, AI chatbots are a helpful tool for productivity, but for those with severe mental illness, they may be a dangerous “echo chamber.” A new study warns that…

Moving Beyond Dopamine to Treat Schizophrenia

Summary: Schizophrenia treatment has been dominated by dopamine-targeting drugs for decades, but these often fail to address the debilitating cognitive and negative symptoms of the disorder. A comprehensive review synthesizes…

Brain Damage in Schizophrenia May Begin in Specific Neural Epicenters

Summary: New brain imaging research shows that structural damage in schizophrenia spectrum disorders may begin in specific “epicenter” regions before spreading across connected brain networks. Individuals with the condition showed…

New Therapy Reshapes Images That Fuel Psychosis

Summary: A new imagery-focused therapy called iMAPS may help people with psychosis gain control over disturbing mental images that fuel paranoia, fear, and hallucinations. In a feasibility trial of 45…