Summary: Researchers at Gladstone Institutes have decoded how parvalbumin (PV) interneurons generate gamma oscillations—the fast brain waves essential for attention and memory—by firing in precise, successive waves rather than all…
Category: Neurology
Higher BMI Linked to Longer Survival After a Dementia Diagnosis
Summary: A long-term study of more than 4,500 older adults reveals that individuals who are overweight or obese when diagnosed with dementia exhibit a significantly lower risk of death than…
Adults With ADHD Face Higher Long-Term Dementia Risk
Summary: A massive study of more than 187,000 older adults enrolled in the NIH’s All of Us Research Program reveals that adults with attention-deficit/hyperactivity disorder (ADHD) face more than quadruple…
Early DBS Protects Cognition in Genetic Parkinson’s
Summary: A multi-center international study reveals that the timing of Deep Brain Stimulation (DBS) surgery is the deciding factor in preserving cognitive function for Parkinson’s disease patients carrying a GBA1…
Could Your Voice Reveal How Fast Your Brain Is Aging?
Summary: A multicenter study of nearly 3,000 individuals published in Science Advances reveals that machine-learning models can infer a person’s biological age and brain health from vocal patterns. This newly…
Central Genetic Switch Controls Long-Distance Axon Navigation
Summary: Challenging the dogma that growing axons navigate exclusively via local cues processed at their tips, neuroscientists have discovered that a centralized genetic switch inside the neuron’s cell body directs…
Brain Activity Predicts Risky Choices Half a Second Before They Are Made
Summary: By recording directly from electrodes implanted in the human orbitofrontal cortex, neuroscientists discovered two neighboring circuits locked in a millisecond-by-millisecond “tug-of-war” between taking a risk and playing it safe.…
How Severe Illness During Pregnancy Alters Fetal Brain Development
Summary: Researchers have discovered that maternal immune activation during pregnancy alters the epigenome of fetal brain cells, disrupting deep-layer neurons and increasing the risk of neurodevelopmental disorders like autism. Key…
Youth Protein TIMP2 Restores Immune Function in the Aging Brain
Summary: Researchers have discovered that the youth-associated protein TIMP2 plays a critical role in maintaining the healthy function of microglia, the brain’s primary immune cells. Supplementing this protein in aged…
