Brain Conductors Find Precise Connection to Target Cells via Protein Handshake

Summary: Researchers have identified two specific proteins, gliomedin and CNTNAP4, that act as a “handshake” mechanism allowing inhibitory chandelier cells to connect precisely with excitatory pyramidal neurons. This connection is…

Immune Signal Ratio May Predict Progressive Multiple Sclerosis

Summary: A long-term study has identified a potential biomarker that could help detect which patients are progressing toward more severe forms of multiple sclerosis. Researchers discovered that a high ratio…

Early Screen Time Linked to Long-Term Brain Changes, Teen Anxiety

Summary: New research following children for more than a decade links high screen exposure before age two to accelerated brain maturation, slower decision-making, and increased anxiety by adolescence. Infants with…

Is Your Oral Bacteria Influencing Multiple Sclerosis?

Summary: High levels of the periodontal bacterium Fusobacterium nucleatum may be associated with more severe disability in people with multiple sclerosis. Researchers analyzed tongue-coating samples and found that MS patients…

Stroke Weakens How the Brain Integrates Speech Sounds

Summary: A new study comparing stroke survivors with healthy adults reveals that post-stroke language disorders stem not from slower hearing but from weaker integration of speech sounds. While patients detected…

Working Nights May Increase Cancer Risk

Summary: Chronic circadian disruption — such as night-shift work, irregular schedules, or frequent jet lag — accelerates the development and spread of aggressive breast cancer. Researchers found that disrupted internal…

Social Isolation Directly Speeds Up Cognitive Decline

Summary: Social isolation has a direct causal impact on how quickly cognitive function declines in later life, independent of whether someone feels lonely. By analyzing more than 137,000 cognitive tests…

Nicotine Withdrawal Makes Smokers More Sensitive to Pain

Summary: A new study shows that abstinent smokers experience heightened pain sensitivity linked to altered activity in specific brain regions. Compared to nonsmokers, abstinent smokers required more postoperative pain relief—especially…

Blocking a Key Protein Greatly Reduces Alzheimer’s Damage

Summary: New findings show that removing Centaurin-α1, a protein elevated in Alzheimer’s disease, significantly reduces inflammation, plaque buildup, and cognitive deficits in a well-established mouse model. Eliminating this protein normalized…

The Way You Drive Might Signal Mild Cognitive Impairment

Summary: Researchers found that long-term driving behavior can reveal early signs of cognitive decline years before clinical diagnosis. Older adults who later developed impairment showed gradual reductions in trip frequency,…