Huntington’s Gene Enhances Early Brain Growth and Intelligence

Summary: A study reveals that the genetic mutation causing Huntington’s disease (HD) enhances brain development and intelligence in early life, but leads to degeneration in adulthood. Children with the HD…

AI Tool Reveals Long COVID May Affect 23% of People

Summary: A new AI tool identified long COVID in 22.8% of patients, a much higher rate than previously diagnosed. By analyzing extensive health records from nearly 300,000 patients, the algorithm…

Key Biochemical Trigger of Huntington’s Disease Progression Identified

Summary: Researchers have identified a crucial biochemical mechanism that could allow Huntington’s disease to be studied before symptoms appear, offering hope for early intervention. The team found that disrupted dopamine…

Dual-Targeting Drug Halts Tau Accumulation in Alzheimer’s

Summary: Scientists have developed a drug that targets both major aggregation-promoting sites of the Tau protein, a key player in Alzheimer’s disease. This peptide inhibitor, RI-AG03, effectively prevents Tau buildup…

ChatGPT Matches Radiologists in Brain Tumor Diagnosis Accuracy

Summary: Researchers compared the diagnostic accuracy of GPT-4 based ChatGPT and radiologists using 150 brain tumor MRI reports. ChatGPT achieved 73% accuracy, slightly outperforming neuroradiologists (72%) and general radiologists (68%).…

Huntington’s Protein Mutation Blocks DNA Repair

Summary: Researchers have discovered that the protein mutated in Huntington’s Disease fails to properly repair DNA, leading to reduced brain cell healing. The huntingtin protein normally stimulates the production of…

Alzheimer’s Drug Faces Scrutiny Over Safety, Efficacy Concerns

Summary: The FDA-approved Alzheimer’s drug donanemab is under scrutiny due to concerns about its effectiveness and safety, according to an investigation. The study highlights multiple patient deaths during trials, design…

Tau Levels Predict Memory Loss in Alzheimer’s

Summary: Alzheimer’s disease (AD) progression varies based on the presence of tau and amyloid-beta (Aβ) proteins in the brain. Patients with high levels of both tau and Aβ experience rapid…

Tau May Protect Brain Cells from Oxidative Damage

Summary: Researchers have discovered that the Tau protein, often linked to neurodegenerative diseases like Alzheimer’s, also has a protective role in the brain. Tau helps combat oxidative stress by aiding…

Morphine’s Pain Relief Mechanism Unveiled

Summary: Researchers have uncovered how morphine relieves pain by activating a specific group of neurons in the brain, termed the ‘morphine ensemble.’ These neurons, located in the rostral ventromedial medulla…