Boosting Wnt Signaling Reverses APOE4 Alzheimer’s Damage

Summary: MIT neuroscientists discovered that the APOE4 gene variant suppresses critical Wnt signaling in oligodendrocytes, trapping essential fatty acids inside toxic lipid droplets rather than deploying them as protective myelin…

New Drug Target Could Freeze Alzheimer’s in Its Tracks

Summary: Researchers discovered a powerful new drug target that could revolutionize how we treat Alzheimer’s disease. By focusing on an enzyme called IDOL, researchers found they could substantially reduce the…