Summary: A new international study reveals a possible connection between GLP1 receptor agonists—used in drugs like Ozempic—and increased risk of depression and suicidal ideation, especially in people with low dopamine…
Category: depression
Depression Speeds Up Physical Illness
Summary: Adults with a history of depression develop long-term physical conditions about 30% faster than those without, according to a large study. Researchers analyzed data from over 172,000 participants and…
How Ketamine Binds to Brain Receptors to Alter Mood
Summary: New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D. Scientists used electron cryo-microscopy to capture how ketamine binds to this…
Dopamine Clock May Drive Bipolar Mood Swings
Summary: New research suggests that mood swings in bipolar disorder are regulated by two clocks: the body’s 24-hour circadian rhythm and a dopamine-based clock that influences alertness. When these clocks…
Masculine Ideals Double Suicide Risk in Men
Summary: Men who strongly adhere to traditional masculine ideologies, such as suppressing emotions and valuing independence, are more than twice as likely to attempt suicide compared to those with more…
Alcohol Use Predicts Escalating Cannabis Vaping Among Youth
Summary: A recent study highlights alcohol as the strongest predictor of cannabis vaping initiation and experimentation among youth and young adults, regardless of demographic factors. Conducted over three years, the…
Depression Alters Brain Circuits, Heightening Negative Perception
Summary: Scientists have identified how depression alters the brain’s response to positive and negative stimuli, particularly in the amygdala, a key emotional processing center. The study found that depression reduces…
Optimism Boosted by Psilocybin, Hinting at Depression Relief
Summary: Researchers have discovered that psilocybin, a psychedelic compound in magic mushrooms, increases optimism and motivation in rats, suggesting potential therapeutic benefits for treating depression. Using computational modeling, scientists observed…
