Summary: While psychedelic research often focuses on hours-long “trips” with psilocybin or LSD, a landmark Phase IIa trial has proven that a much shorter experience can be just as potent.…
Category: depression
How the Brain Distinguishes Instant Treats from Long-Term Triumphs
Summary: Researchers have unveiled new insights into a specific brain signal known as “Reward Positivity,” which may bridge the gap between simple pleasure and complex goal-setting. This electrical burst, occurring…
Depression Quietly Damages the Heart Through Stress Circuits
Summary: Depression and anxiety may heighten cardiovascular disease risk through chronic stress pathways in the brain and body. In a large analysis of more than 85,000 adults, those with depression…
Anti-Inflammatory Treatments Show Promise for Depression
Summary: A new analysis shows that anti-inflammatory medications may help reduce symptoms for a subset of people with depression who also have chronic, low-grade inflammation. By reviewing randomized controlled trials…
Abuse Survivors Show Unique Injury Signatures Tied to Suicide Risk
Summary: A new study finds that victims of intimate partner violence who also experience suicidal thoughts or behaviors show distinct and severe injury patterns on medical imaging. These patients were…
Genetics Point to a New Type of Suicide Risk
Summary: New research shows that many people who die by suicide without prior suicidal thoughts or behaviors are not simply “missed cases”—they may have an entirely different underlying risk profile.…
Stress-Like Behaviors Traced to a Single ATP Circuit in the Brain
Summary: New research reveals that reduced ATP signaling in the hippocampus plays a causal role in both depression- and anxiety-like behaviors. In stressed male mice, ATP levels and the ATP-releasing…
Shocking Disparities: Women Face Higher Risk of ECT
Summary: A large international survey of 858 electroconvulsive therapy recipients found that women are twice as likely as men to receive ECT and experience more adverse effects. Women reported higher…
Genetic Roots of Depression Reveal Strong Suicide Risk Signals
Summary: New research shows that depression beginning before age 25 has a much stronger hereditary component than depression that emerges later in life. By analyzing genetic data from over 150,000…
Common Antidepressant Eases Core Symptoms Within Two Weeks
Summary: A new analysis of the PANDA clinical trial reveals that sertraline, one of the most prescribed antidepressants, improves key emotional symptoms of depression—such as sadness, self-loathing, and suicidal thoughts—within…
