Summary: Classical psychedelics like LSD, psilocybin, and mescaline are known for activating the 5-HT2A serotonin receptor, but a new study reveals their effects go far beyond. Researchers profiled 41 psychedelics…
Category: dopamine
Low Sodium Linked to Anxiety Through Brain Chemistry Disruption
Summary: Chronic hyponatremia—long viewed as symptomless—is now shown to disrupt brain chemistry and cause anxiety-like behaviors, according to a new study in mice. Researchers found that prolonged low sodium levels…
Shared Genetic Signatures Found Across Psychiatric Disorders
Summary: Researchers have uncovered shared biological mechanisms across major psychiatric disorders by analyzing postmortem brain samples from the dorsolateral prefrontal cortex. Instead of looking at gene expression broadly, they zoomed…
Vitamin B1 Derivative Sparks Dopamine, Boosts Wakefulness
Summary: Thiamine derivatives, once developed to treat nutrient deficiencies, are now being explored for their potential effects on brain function and energy. A new study shows that TTFD, a thiamine…
Potential Depression Risk Linked to Ozempic-Like Drugs
Summary: A new international study reveals a possible connection between GLP1 receptor agonists—used in drugs like Ozempic—and increased risk of depression and suicidal ideation, especially in people with low dopamine…
Dopamine Clock May Drive Bipolar Mood Swings
Summary: New research suggests that mood swings in bipolar disorder are regulated by two clocks: the body’s 24-hour circadian rhythm and a dopamine-based clock that influences alertness. When these clocks…
Childhood Stress Disrupts Attention, Sleep, and Dopamine Balance in Adults
Summary: New research links childhood adversity with later attention deficits, sleep disruptions, and specific dopamine imbalances in the brain. Focusing on critical developmental windows, scientists found that disrupted care early…
Unexpected Sounds Boost Dopamine, Leading to Riskier Decisions
Summary: A new study shows that unexpected sounds can cause dopamine bursts in the brain, which may lead to riskier decision-making. Researchers found that participants were 4% more likely to…
Love’s Chemistry: How Dopamine Shapes Bonds and Breakups
Summary: Researchers uncover how dopamine, a key neurotransmitter, varies in response to social interactions, distinguishing between intimate and casual relationships. Their research, conducted on prairie voles, sheds light on the…
Sleepless Nights: The Brain’s Surprising Reaction to All-Nighters
Summary: unveiled the science behind the buoyant mood many feel after acute sleep deprivation, like pulling an all-nighter. The study in mice showed that not only does dopamine release rise…